Giants of Pharmaceutical Sciences

A collection of special issues presented by the Journal of Pharmaceutical Sciences

The editors of the Journal of Pharmaceutical Sciences invite you to look back at the Giants of Pharmaceutical Sciences, a special virtual issue collection of all dedicated issues of the journal honoring the preeminent pharmaceutical scientists in the recent history of the field. The featured scientists have made a lasting impact on the field and the journal is honored to continue to celebrate their significant contributions to research, teaching, and service. This dedicated virtual issue will remain open to the public and each year the editors will select another giant of pharmaceutical science to honor and include in the issue.

Click on the picture below to start reading the special issue dedicated to each Giant of Pharmaceutical Sciences or read articles authored by these prominent scientists.

Physical Stability of Proteins in Aqueous Solution – Mechanism and Driving Forces in Non-native Protein Aggregation
Pharmaceutical Research, 20(9), 1325-1336

  • Influence of particle size and antigen binding on effectiveness of aluminum salt adjuvants in a model lysozyme vaccine

    Vol. 97, Issue 12, p5252–5262
  • Subvisible Particle Counting Provides a Sensitive Method of Detecting and Quantifying Aggregation of Monoclonal Antibody Caused by Freeze-Thawing: Insights Into the Roles of Particles in the Protein Aggregation Pathway

    Vol. 100, Issue 2, p492–503
  • Pharmaceutical Applications of Cyclodextrins. 1. Drug Solubilization and Stabilization

    Thorsteinn Loftsson, Marcus E. Brewster
    Vol. 85, Issue 10, p1017–1025
  • Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?

    Joachim Brouwers, Marcus E Brewster, Patrick Augustijns
    Vol. 98, Issue 8, p2549–2572
  • Characterization of the interaction of 2‐hydroxypropyl‐β‐cyclodextrin with itraconazole at pH 2, 4, and 7

    Jef Peeters, Peter Neeskens, Jan P. Tollenaere, Pieter Van Remoortere, Marcus E. Brewster
    Vol. 91, Issue 6, p1414–1422

  The use of solubility parameters in pharmaceutical dosage form design
  B.C. Hancock, P. York, R.C. Rowe
  Int. J. Pharm. 148, 1-21 (1997)
  Full-text HTML on ScienceDirect

  Crystallization processes in pharmaceutical technology and drug delivery design
  B. Shekunov, P. York
  J. Crystal Growth, 211, (122-136 (2000)
  Full-text HTML on ScienceDirect

  • Data Mining of Fractured Experimental Data Using Neurofuzzy Logic–Discovering and Integrating Knowledge Hidden in Multiple Formulation Databases for a Fluid-Ded Granulation Process

    Q. Shao, R.C. Rowe, P. York
    Vol. 97, Issue 6, p2091–2101
  • Investigation of the Effect of the Uneven Distribution of CYP3A4 and P-Glycoprotein in the Intestine on the Barrier Function against Xenobiotics: A Simulation Study

    Takao Watanabe, Kazuya Maeda, Chikako Nakai, Yuichi Sugiyama
    Vol. 102, Issue 9, p3196–3204
  • An Assessment of the Oral Bioavailability of Three Ca-Channel Blockers Using a Cassette-Microdose Study: A New Strategy for Streamlining Oral Drug Development

    Shinji Yamashita, Makoto Kataoka, Yuki Suzaki, Hiromitsu Imai, Takuya Morimoto, Kyoichi Ohashi, Akihiro Inano, Kazutaka Togashi, Kuninori Mutaguchi, Yuichi Sugiyama
    Vol. 104, Issue 9, p3154–3161
  • Development of a Support Vector Machine-Based System to Predict Whether a Compound Is a Substrate of a Given Drug Transporter Using Its Chemical Structure

    Atsushi Ose, Kota Toshimoto, Kazushi Ikeda, Kazuya Maeda, Shuya Yoshida, Fumiyoshi Yamashita, Mitsuru Hashida, Takashi Ishida, Yutaka Akiyama, Yuichi Sugiyama
    Vol. 105, Issue 7, p2222–2230
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